Guanylin (human)

Name: Guanylin (human)
Brand: Tocris Bioscience
SKU: 1898
Price: 348 USD
Availability: InStock

Tocris Bioscience | Catalog # 1898

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Endogenous activator of intestinal guanylyl cyclase

Technical Data
Reviews

Product Description
Product Specifications
Solubility
Calculators
Background References
Product Documents
Specific Notices

Key Product Details

Description

Endogenous activator of intestinal guanylyl cyclase

View all Guanylyl Cyclase Activators »

Product Description

Guanylin (human) is an endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.

Product Specifications for Guanylin (human)

Molecular Weight

1458.65

Formula

C₅₈H₈₇N₁₅O₂₁S₄

Storage

Store at -20°C

Purity

≥95% (HPLC)

CAS Number

183200-12-6

PubChem ID

90488722

InChI Key

XPNQMTAYRNMRRD-RDJGHUJSSA-N

SMILES

[H]N1CCC[C@H]1C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@H]1CSSC[C@@H]2NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC3=CC=C(O)C=C3)NC(=O)[C@H](C)NC(=O)[C@H](CSSC[C@H](NC(=O)CNC(=O)[C@@H](NC2=O)[C@@H](C)O)C(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CCC(O)=O)NC1=O)[C@@H](C)CC

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Soluble to 1mg/ml in water

Calculators

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Background References

References are publications that support the biological activity of the product.

Currie Guanylin: an endogenous activator of intestinal guanylate cyclase. Proc.Natl.Acad.Sci.U.S.A. 1992 PMID: 1346555
Nokihara Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer. Regul.Pept. 1997 PMID: 9272623
Beltowski Guanylin and related peptides. J.Physiol.Pharmacol. 2001 PMID: 11596856

Product Documents for Guanylin (human)

Certificate of Analysis

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Product Specific Notices for Guanylin (human)

For research use only

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