Endogenous peptide activator of intestinal guanylyl cyclase; secreted mainly by the gastrointestinal mucosa. Regulates water and electrolyte transport in intestinal and renal epithelia.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Guanylin and related peptides.
Guanylin: an endogenous activator of intestinal guanylate cyclase.
Currie et al.
Synthesis, solution structure, binding activity, and cGMP activation of human guanylin and its disulfide isomer.
Nokihara et al.