Potent, selective inhibitor of the NGF receptor tyrosine kinase A (TrkA) (IC50
= 2 nM). Displays > 100-fold selectivity over a range of other kinases.
Soluble to 15 mM in DMSO
Store at RT
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All Tocris products are intended for laboratory research use only.
Sold for research purposes under agreement from GlaxoSmithKline.
Discovery and in vitro evaluation of potent TrkA kinase inhibitors: oxindole and aza-oxindoles.
Wood et al.
The citations listed below are publications that use Tocris products. Selected citations for GW 441756 include:
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