GYY 4137 morpholine salt
Chemical Name: P-(4-Methoxyphenyl)-P-4-morpholinylphosphinodithioic acid morpholine salt
Biological ActivityGYY 4137 morpholine salt is a slow-releasing H2S donor. Exhibits vasodilator and antihypertensive activity. Activity causes slow dilation of blood vessels in vitro and in vivo; does not influence vascular smooth muscle cell viability in culture. Water-soluble.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Characterization of a novel, water-soluble hydrogen sulfide-releasing molecule (GYY4137).
Li et al.
The effect of hydrogen sulfide donors on lipopolysaccaride-induced formation of inflammatory mediators in macrophages.
Whiteman et al.
The slow-releasing hydrogen sulfide donor, GYY4137, exhibits novel anti-cancer effects in vitro and in vivo.
Lee et al.
PLoS One, 2011;6:e21077
Hydrogen sulfide donor, GYY4137, exhibits anti-atherosclerotic activity in high fat fed apolipoprotein E-/- mice.
Liu et al.
Br.J.Pharmacol. [Epub ahead of print], 2013;
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