H2DCFDA (CAS 4091-99-0): R&D Systems
Catalog Number: 5935
Chemical Name: 2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic acid
Biological Activity
Fluorescent ROS indicator; becomes fluorescent when oxidized. Excitation wavelength ~490 nm, emission ~520 nm. Cell permeable.
Technical Data
  • M.Wt:
    487.29
  • Formula:
    C24H16Cl2O7
  • Solubility:
    Soluble to 100 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >97%
  • Storage:
    Store at -20°C
  • CAS No:
    4091-99-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Sigma-2 receptors play a role in cellular metabolism: stimulation of glycolytic hallmarks by CM764 in human SK-N-SH neuroblastoma.
    Nicholson et al.
    J.Pharmacol.Exp.Ther., 2013;356:232
  2. ROS-induced JNK and p38 signaling is required for unpaired cytokine activation during drosophila regeneration.
    Santabárbara-Ruiz et al.
    PLoS Genet., 2015;11:e1005595
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