H2DCFDA
Chemical Name: 2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic acid
Purity: ≥95%
Biological Activity
H2DCFDA is a fluorescent ROS indicator; becomes fluorescent when oxidized. Excitation wavelength ~490 nm, emission ~520 nm. Cell permeable.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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Background References
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Sigma-2 receptors play a role in cellular metabolism: stimulation of glycolytic hallmarks by CM764 in human SK-N-SH neuroblastoma.
Nicholson et al.
J.Pharmacol.Exp.Ther., 2013;356:232 -
ROS-induced JNK and p38 signaling is required for unpaired cytokine activation during drosophila regeneration.
Santabárbara-Ruiz et al.
PLoS Genet., 2015;11:e1005595
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