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hCAII Degrader 11

Catalog #: 7964 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7964/2

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hCAII Degrader 11 | CAS No. 2892306-56-6 | Active Degraders
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Description: Potent human carbonic anhydrase II Degrader (PROTAC®)

Chemical Name: 4-(Aminosulfonyl)-N-[12-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]dodecyl]benzamide

Purity: ≥98%

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Biological Activity

hCAII Degrader 11 is a potent human carbonic anhydrase II (hCAII) Degrader (PROTAC®; Dmax = 100% at 5 nM, DC50 = 0.5 nM).

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Sold with kind permission of Professor Cohen and Professor Burkart, Department of Chemistry and Biochemistry, University of California, USA.

Technical Data

M.Wt:
639.77
Formula:
C32H41N5O7S
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2892306-56-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold with kind permission of Professor Cohen and Professor Burkart

Product Datasheets

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