Biological ActivityHelianorphin-19 is a high affinity, potent and selective G protein-biased κ-opioid receptor (KOR) agonist (Ki = 25 nM; EC50 = 45 nM). Helianorphin-19 exhibits approximately 200-fold selectivity for KOR over μ and δ-opioid receptors. In vivo Helianorphin-19 shows potent peripheral analgesic efficacy in a mouse model of visceral pain without affecting motor coordination/sedation.
(Modifications: Cyclic peptide, Disulfide bridge: 1-9]
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
No product specific FAQs exist for this product, however you mayView all Peptide FAQs
Reviews for Helianorphin-19
There are currently no reviews for this product. Be the first to review Helianorphin-19 and earn rewards!
Have you used Helianorphin-19?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image