Catalog Number: 1579
Chemical Name: 2-(1-Hexynyl)-N-methyladenosine
Biological Activity
High affinity and selective adenosine A3 receptor agonist (Ki values are 1.1, 327, 1230 and > 30,000 nM for human A3, A1, A2A and A2B receptors respectively).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • Purity:
  • Storage:
    Desiccate at +4°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. [3H]HEMADO- a novel tritated agonist selective for the human adenosine A3-receptor.
    Klotz et al.
    Eur.J.Pharmacol., 2006;556:14
  2. N6-Alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A3 receptor and a starting point for searching A2B ligands
    Volpini et al.
    J.Med.Chem., 2002;45:3271

The citations listed below are publications that use Tocris products. Selected citations for HEMADO include:

Showing Results 1 - 2 of 2

  1. Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.
    Authors: Stoddart Et al.
    Chem Biol
  2. Disparity in FcηRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine.
    Authors: Gomez Et al.
    Mol Cell Proteomics
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