Chemical Name: 2-(1-Hexynyl)-N-methyladenosine
Biological ActivityHigh affinity and selective adenosine A3 receptor agonist (Ki values are 1.1, 327, 1230 and > 30,000 nM for human A3, A1, A2A and A2B receptors respectively).
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
[3H]HEMADO- a novel tritated agonist selective for the human adenosine A3-receptor.
Klotz et al.
N6-Alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A3 receptor and a starting point for searching A2B ligands
Volpini et al.
Citations for HEMADO
The citations listed below are publications that use Tocris products. Selected citations for HEMADO include:
2 Citations: Showing 1 - 2
Fragment screening at adenosine-A(3) receptors in living cells using a fluorescence-based binding assay.
Authors: Stoddart Et al.
Chem Biol 2012;19:1105
Disparity in FcηRI-induced degranulation of primary human lung and skin mast cells exposed to adenosine.
Authors: Gomez Et al.
Mol Cell Proteomics 2011;31:479
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