HEMADO

Key Product Details

Product Description

HEMADO is a high affinity and selective adenosine A₃ receptor agonist (K_i values are 1.1, 327, 1230 and > 30,000 nM for human A₃, A₁, A_2A and A_2B receptors respectively).

Product Specifications for HEMADO

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for HEMADO

The following data is based on the product molecular weight 361.40.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.77 mL	13.84 mL	27.67 mL
5 mM	0.55 mL	2.77 mL	5.53 mL
10 mM	0.28 mL	1.38 mL	2.77 mL
50 mM	0.06 mL	0.28 mL	0.55 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 8 publications citing the usage of this product.

• Volpini N⁶-Alkyl-2-alkynyl derivatives of adenosine as potent and selective agonists at the human adenosine A₃ receptor and a starting point for searching A_2B ligands J.Med.Chem. 2002 PMID: 12109910
• Klotz [³H]HEMADO- a novel tritated agonist selective for the human adenosine A₃-receptor. Eur.J.Pharmacol. 2006 PMID: 17126322

Product Documents for HEMADO