Catalog Number: 3791
Biological Activity
Bioactive endogenous peptide substrate for endopeptidase 24.15 (ep24.15), neurolysin (ep24.16) and ACE. Ki values are 27.76, 3.43 and 1.87 μM respectively. Potent hypotensive in vivo. Also acts as a selective CB1 receptor inverse agonist. Displays antinociceptive activity in vivo.
Technical Data
  • M.Wt:
    1054.26
  • Formula:
    C50H79N13O12
  • Sequence:
    PVNFKLLSH
  • Solubility:
    Soluble to 1 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1314035-51-2
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Novel natural peptide substrates for endopeptidase 24.15, neurolysin, and angiotensin-converting enzyme.
    Rioli et al.
    J.Biol.Chem., 2003;278:8547
  2. Hypotensive effects of hemopressin and bradykinin in rabbits, rats and mice. A comparative study.
    Blais et al.
    Peptides, 2005;26:1317
  3. Hemopressin is an inverse agonist of CB1 cannabinoid receptors.
    Heimann et al.
    Proc.Natl.Acad.Sci.USA, 2007;104:20588

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