Herbimycin A

   
Product Datasheet
Catalog Number:1629
Chemical Name:(15R)-17-demethoxy-15-methoxy-11-O-methyl-geldanamycin
Product Details
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Biological Activity
Ansamycin antibiotic that acts as a Src family kinase inhibitor. Binds to the SH domain and inhibits the activity of p60v-src and p210BCR-ABL. Exhibits antiangiogenic activity in endothelial cells in vitro. Also inhibits Hsp90 and impairs recovery from heat shock.
Technical Data
  • M.Wt:
    574.67
  • Formula:
    C30H42N2O9
  • Solubility:
    Soluble to 10 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at -20°C
  • CAS No:
    70563-58-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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