Inhibitor of furin (Ki
values are 0.106, 0.58 and 13.2 μ
M for furin, PACE4 and PC1 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Hexa-D-arginine treatment increases 7B2.PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.
Yuan et al.
J.Bone Miner.Res., 2012;28:56
Polyarginines are potent furin inhibitors.
Cameron et al.