Catalog Number: 4711
Biological Activity
Inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).
Technical Data
  • M.Wt:
    954.16
  • Formula:
    C36H75N25O6
  • Sequence:
    RRRRRR

    (Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6=D-Arg)

  • Solubility:
    Soluble to 2 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    673202-67-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Polyarginines are potent furin inhibitors.
    Cameron et al.
    J.Biol.Chem., 2000;275:36741
  2. Hexa-D-arginine treatment increases 7B2.PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.
    Yuan et al.
    J.Bone Miner.Res., 2012;28:56

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