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Description: Furin inhibitor
Product Details
Citations (1)

Biological Activity

Inhibitor of furin (Ki values are 0.106, 0.58 and 13.2 μM for furin, PACE4 and PC1 respectively).

Technical Data


(Modifications: Arg-6 = C-terminal amide, Arg-1,2,3,4,5,6=D-Arg)

Soluble to 2 mg/ml in water
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Hexa-D-arginine treatment increases 7B2.PC2 activity in hyp-mouse osteoblasts and rescues the HYP phenotype.
    Yuan et al.
    J.Bone Miner.Res., 2012;28:56
  2. Polyarginines are potent furin inhibitors.
    Cameron et al.
    J.Biol.Chem., 2000;275:36741

Product Datasheets

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Citation for Hexa-D-arginine

The citations listed below are publications that use Tocris products. Selected citations for Hexa-D-arginine include:

1 Citation: Showing 1 - 1

  1. Biowire Model of Interstitial and Focal Cardiac Fibrosis.
    Authors: Wang Et al.
    ACS Cent Sci  2019;5:1146


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