HIP1 Antibody (SR1072) - BSA Free

Novus Biologicals | Catalog # NBP3-21916

Recombinant Monoclonal Antibody
Novus Biologicals
100% Guarantee

Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1072 expressed in HEK293

Format

BSA Free
View all HIP1 Primary Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human HIP1 (Uniprot #: O00291)

Specificity

Detects endogenous levels of total HIP1

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

116 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for HIP1 Antibody (SR1072) - BSA Free

Western Blot: HIP1 Antibody (SR1072) [NBP3-21916] -

Western Blot: HIP1 Antibody (SR1072) [NBP3-21916] - Western blot analysis using NBP3-21916 in Jurkat cell lysate.

Applications for HIP1 Antibody (SR1072) - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunoprecipitation

1:30

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: HIP1

Huntingtin Interacting Protein (HIP1) is a reportedly proapoptotic, cargo-specific adaptor protein that may be involved in the pathogenesis of Huntingtin's disease. Huntingtin's is a neurodegenerate disease caused by the expansion of a polymorphic glutamine tract in Huntingtin.

In addition to playing a role in Huntingtin disease, HIP1 is likely to be involved in the recruitment of clathrin coats to lipid membranes, and it may also factor in tumorigenesis by allowing the survival of precancerous and cancerous cells. Since HIP-1 expression is significantly associated with prostate and colon cancer metastasis, HIP-1 can serve as a putative prognostic factor for prostate and colon cancers.

Alternate Names

HIP-1, HIP-I, huntingtin interacting protein 1, huntingtin-interacting protein 1, Huntingtin-interacting protein I, ILWEQ, MGC126506

Gene Symbol

HIP1

Additional HIP1 Products

Product Documents for HIP1 Antibody (SR1072) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

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Product Specific Notices for HIP1 Antibody (SR1072) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Protocols

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FAQs

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