Chemical Name: 2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole
Biological ActivityHJC 0350 is a selective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
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Identification and characterization of small molecules as potent and specific EPAC2 antagonists.
Chen et al.
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