Chemical Name: 2,4-Dimethyl-1-[(2,4,6-trimethylphenyl)sulfonyl]-1H-pyrrole
Biological ActivitySelective Epac2 inhibitor (IC50 = 0.3 μM). Displays no effect on Epac1. Blocks stimulation of the Epac2-FL FRET sensor in HEK293 cells.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Identification and characterization of small molecules as potent and specific EPAC2 antagonists.
Chen et al.
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