Human beta-1,3-N-acetylglucosaminyl-transferase 2/B3GNT2 Alexa Fluor® 647-conjugated Antibody

Catalog #: FAB3960R Datasheet / COA / SDS

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FAB3960R-100UG

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All Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2 Antibodies

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Human beta-1,3-N-acetylglucosaminyl-transferase 2/B3GNT2 Alexa Fluor® 647-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human beta -1,3-N-acetylglucosaminyltransferase 2/B3GNT2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human B4GALT1 is observed

Source

Monoclonal Mouse IgG2b Clone # 485327

Purification

Protein A or G purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant human Î²-1,3-N-acetylglucosaminyltransferase 2/B3GNT2
Lys29-Cys397
Accession # Q9NY97

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 647 (Excitation= 650 nm, Emission= 668 nm)

Applications

Recommended Concentration

Sample

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Beta-1,3-N-Acetylglucosaminyltransferase 2/B3GNT2

beta 1,3-Linked GlcNAc residues are present in the backbone of various biologically important glycans which are involved in many essential biological functions such as keratan sulfate synthesis in corneal tissue (1). The addition of such residues are catalyzed by a family of beta 1,3‑N‑acetylglucosaminyltransferases, that includes at least eight members (1‑5). All of them are type II Golgi resident transmembrane proteins and have high homology to the beta 1,3-galactosyltransferase family. beta 1,3‑N‑acetylglucosaminyltransferases 2 or beta 3GNT2 prefers the substrate lacto-N-neotetraose and is involved in the biosynthesis of poly-N-acetyllactosamine chains (6).

Long Name

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyl-transferase 1

Entrez Gene IDs

10678 (Human); 53625 (Mouse)

Alternate Names

B3Galt6; B3GALT7; b3Gal-T7; B3GNT; B3GNT1; B3GN-T1; B3GNT2; B3GN-T2; B3GNT-2; Beta-1,3-galactosyltransferase 7; Beta-1,3-GalTase 7; Beta-1,3-Gn-T1; Beta-1,3-Gn-T2; Beta-1,3-N-acetylglucosaminyltransferase 1; Beta-1,3-N-acetylglucosaminyltransferase 2; beta-1,3-N-acetylglucosaminyltransferase bGnT-1; beta-1,3-N-acetylglucosaminyltransferase bGnT-2; Beta3GalT7; Beta3Gal-T7; BETA3GNT; Beta3gnt1; Beta3Gn-T1; Beta3Gn-T2; Beta-3-Gx-T7; BGnT-1; BGNT2; BGnT-2; EC 2.4.1.-; UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7; UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1; UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2