Human CCL23/MPIF-1 Antibody Summary
Accession # P55773
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Chemotaxis Induced by CCL23/MPIF‑1 and Neutral-ization by Human CCL23/MPIF‑1 Antibody. Recombinant Human CCL23/MPIF-1 (Catalog # 371-MP) chemoattracts the THP-1 human acute monocytic leukemia cell line in a dose-dependent manner (orange line). The amount of cells that migrated through to the lower chemotaxis chamber was measured by Resazurin (Catalog # AR002). Chemotaxis elicited by Recombinant Human CCL23/MPIF-1 (1 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human CCL23/MPIF-1 Monoclonal Antibody (Catalog # MAB371). The ND50is typically 2-6 µg/mL.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
CCL23, also known as Myeloid Progenitor Inhibitory Factor-1 (MPIF-1), is a CC chemokine that is produced by some myeloid cell lines and monocyte-derived dendritic cells. It binds CCR1 and inhibits the differentiation of progenitor cells that give rise to granulocytes and macrophages. CCL23 is also chemotactic for resting T cells, neutrophils, monocytes and dendritic cells.
Citation for Human CCL23/MPIF-1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
CCL23 expression is induced by IL-4 in a STAT6-dependent fashion.
Authors: Novak H, Muller A, Harrer N, Gunther C, Carballido JM, Woisetschlager M
J. Immunol., 2007;178(7):4335-41.
Sample Types: Cell Culture Supernates
Applications: ELISA Development
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