Human CD37 Alexa Fluor® 750-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB4625S-100UG
R&D Systems Antibodies
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Human CD37 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human CD37. Stains human CD37 transfectants but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2a Clone # 424925
Immunogen
Mouse myeloma cell line NS0-derived recombinant human CD37 Accession # Q96LM7
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 750

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
Human whole blood monocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Data Example

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 degreesC. Do not use past expiration date.

Background: CD37

CD37, also known as TSPAN26, is a 40-45 kDa palmitoylated tetraspanin superfamily glycoprotein that is expressed by lymphocytes and myeloid cells. CD37 directly associates with dectin-1 on macrophages and stabilizes cell surface dectin-1 expression. It also inhibits T cell activation and proliferation by limiting T cell receptor signaling. Human CD37 shares 80% aa sequence identity with mouse and rat CD37.

Entrez Gene IDs
951 (Human); 12493 (Mouse); 29185 (Rat)
Alternate Names
CD37 antigentetraspanin-26; CD37 molecule; CD37; cell differentiation antigen 37; GP52-40; leukocyte antigen CD37; MGC120234; Tetraspanin-26; TSPAN26; tspan-26; TSPAN26leukocyte surface antigen CD37

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