Human Chondromodulin-1 Alexa Fluor® 350-conjugated Antibody

Catalog #: FAB41681U Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB41681U-100UG

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Human Chondromodulin-1 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Chondromodulin‑1 in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG2b Clone # 394002
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Chondromodulin‑1 mature chain
Glu215-Val333
Accession # NP_001011705.1
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 350 (Excitation= 346 nm, Emission= 442 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Chondromodulin-1

Chondromodulin-1 (ChM-1), also known as Lect1, is a type II transmembrane protein that is cleaved intracellularly resulting in the secretion of a 25 kDa molecule. ChM-1 is expressed in avascular cartilage, cardiac valves, and the eye. The antiangiogenic properties of ChM-1 can block tumor progression and the pathological vascularization of cardiac valves. Human ChM-1 shares 89%‑92% aa sequence identity with bovine, mouse, rabbit, and rat ChM-1.

Entrez Gene IDs
11061 (Human); 16840 (Mouse); 81512 (Rat)
Alternate Names
BRICD3; BRICHOS domain containing 3; ChM-1; CHM1chondromodulin I; CHMI; CHM-I; chondromodulin; Chondromodulin1; Chondromodulin-1; chondromodulin-I; LECT1; leukocyte cell derived chemotaxin 1; Leukocyte cell-derived chemotaxin 1; multiple myeloma tumor suppressor 1; MYETS1

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