Human Chondromodulin-1 Alexa Fluor® 750-conjugated Antibody Summary
Glu215-Val333
Accession # NP_001011705.1
Applications
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
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Preparation and Storage
Background: Chondromodulin-1
Chondromodulin-1 (ChM-1), also known as Lect1, is a type II transmembrane protein that is cleaved intracellularly resulting in the secretion of a 25 kDa molecule. ChM-1 is expressed in avascular cartilage, cardiac valves, and the eye. The antiangiogenic properties of ChM-1 can block tumor progression and the pathological vascularization of cardiac valves. Human ChM-1 shares 89%‑92% aa sequence identity with bovine, mouse, rabbit, and rat ChM-1.
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