Chondromodulin-1 (ChM-1), also known as Lect1, is a type II transmembrane protein that is cleaved intracellularly resulting in the secretion of a 25 kDa molecule. ChM-1 is expressed in avascular cartilage, cardiac valves, and the eye. The antiangiogenic properties of ChM-1 can block tumor progression and the pathological vascularization of cardiac valves. Human ChM-1 shares 89%‑92% aa sequence identity with bovine, mouse, rabbit, and rat ChM-1.
Human Chondromodulin‑1 Antibody
R&D Systems | Catalog # MAB41681
Key Product Details
Species Reactivity
Validated:
Human
Cited:
Human
Applications
Validated:
Western Blot
Cited:
Western Blot
Label
Unconjugated
Antibody Source
Monoclonal Mouse IgG2B Clone # 394002
Loading...
Product Specifications
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Chondromodulin‑1 mature chain
Glu215-Val333
Accession # NP_001011705.1
Glu215-Val333
Accession # NP_001011705.1
Specificity
Detects human Chondromodulin‑1 in direct ELISAs and Western blots.
Clonality
Monoclonal
Host
Mouse
Isotype
IgG2B
Applications for Human Chondromodulin‑1 Antibody
Application
Recommended Usage
Western Blot
1 µg/mL
Sample: Recombinant Human Chondromodulin‑1
Sample: Recombinant Human Chondromodulin‑1
Formulation, Preparation, and Storage
Purification
Protein A or G purified from hybridoma culture supernatant
Reconstitution
Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.
Loading...
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Shipping
Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Calculators
Background: Chondromodulin-1
Alternate Names
BRICD3, ChM-1, Chondromodulin1, LECT1
Gene Symbol
CNMD
UniProt
Additional Chondromodulin-1 Products
Product Documents for Human Chondromodulin‑1 Antibody
Product Specific Notices for Human Chondromodulin‑1 Antibody
For research use only
Citations for Human Chondromodulin‑1 Antibody
Customer Reviews for Human Chondromodulin‑1 Antibody
There are currently no reviews for this product. Be the first to review Human Chondromodulin‑1 Antibody and earn rewards!
Have you used Human Chondromodulin‑1 Antibody?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Cellular Response to Hypoxia Protocols
- R&D Systems Quality Control Western Blot Protocol
- Troubleshooting Guide: Western Blot Figures
- Western Blot Conditions
- Western Blot Protocol
- Western Blot Protocol for Cell Lysates
- Western Blot Troubleshooting
- Western Blot Troubleshooting Guide
- View all Protocols, Troubleshooting, Illustrated assays and Webinars