Home / Exostosin-like 3/EXTL3 / Human Exostosin-like 3/EXTL3 Alexa Fluor® 750-conjugated Antibody

Human Exostosin-like 3/EXTL3 Alexa Fluor® 750-conjugated Antibody

Catalog #: FAB2635S Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
FAB2635S-100UG

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Human Exostosin-like 3/EXTL3 Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human Exostosin-like 3/EXTL3 in direct ELISAs and Western blots.
Source
Monoclonal Mouse IgG2a Clone # 311007
Purification
Protein A or G purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant human Exostosin-like 3/EXTL3
Thr52-Ile919
Accession # O43909
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunoprecipitation
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Exostosin-like 3/EXTL3

EXTL3 is an ER-resident type II transmembrane protein belonging to the EXT family of tumor suppressor genes. EXT family members are glycosyl transferases that are involved in the synthesis of the glycosaminoglycan chains of heparan sulfate proteoglycans. EXTL3 was also reported to be a receptor for the REG protein, a pancreatic beta-cell regeneration factor. The amino acid sequence of rhEXTL3 is 98%, 97%, 88%, and 83% identical to that of dog, rat/mouse, Xenopus and zebrafish.

Entrez Gene IDs
2137 (Human)
Alternate Names
botv; DKFZp686C2342; EC 2.4.1.223; exostoses (multiple)-like 3; Exostosin like 3; Exostosin-like 3; EXTL1L; EXTL3; EXTR1BOTV; EXT-related protein 1; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Hereditary multiple exostoses gene isolog; KIAA0519; Multiple exostosis-like protein 3; Putative tumor suppressor protein EXTL3; reg receptor; REG; REGR; RPR

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