Human GLI-3 Alexa Fluor® 405-conjugated Antibody

Catalog #: FAB3690V Datasheet / COA / SDS

Recombinant Monoclonal Antibody

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FAB3690V-100UG

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All GLI-3 Antibodies

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human GLI-3 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity

Human

Specificity

Detects human GLI-3 in direct ELISAs.

Source

Monoclonal Rabbit IgG Clone # 2352B

Purification

Protein A or G purified

Immunogen

E. coli-derived recombinant human GLI-3
Met1-Glu479
Accession # P10071

Formulation

Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Label

Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration

Sample

Immunocytochemistry

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: GLI-3

GLI3 is a zinc finger protein. The GLI family of proteins are transcription factors and are mediators of Sonic hedgehog signaling. GLI3 is known to be a transcriptional repressor but also may have a positive transcription function. Mutations in the GLI3 gene are associated with many polydactyly diseases.

Long Name

GLI-Kruppel family member GLI3

Entrez Gene IDs

2737 (Human); 14634 (Mouse); 140588 (Rat)

Alternate Names

ACLS; ACLSPAPAPHS; ADD; Bph; GCPS; GLI family zinc finger 3; GLI3 form of 190 kDa; GLI3 full length protein; GLI3; GLI-3; GLI3-190; GLI3FL; GLI-Kruppel family member GLI3; glioma-associated oncogene family zinc finger 3; Greig cephalopolysyndactyly syndrome; oncogene GLI3; PAP-A; PAPA1; PAPB; PAPBDNA-binding protein; Pdn; PHS; PPDIV; Xt; zinc finger protein GLI3