Human ITFG1 APC-conjugated Antibody Summary
Accession # Q8TB96
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of ITFG1 in K562 Human Cell Line by Flow Cytometry. K562 human chronic myelogenous leukemia cell line was stained with Mouse Anti-Human ITFG1 APC‑conjugated Monoclonal Antibody (Catalog # FAB89001A, filled histogram) or isotype control antibody (Catalog # IC0041A, open histogram). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
- 12 months from date of receipt, 2 to 8 °C as supplied.
Integrin-alpha FG-GAP repeat-containing protein 1 (ITFG1), also known as T cell immunomodulatory protein (TIP), was initially identified using bioinformatics and high-throughput cell-based screening assays to isolate novel factors involved in T cell biology. Ubiquitously expressed as a 96-100 kDa glycoprotein (it is absent on T cells, B cells, and monocytes), ITFG1 would appear to be a type I transmembrane protein that contains a 534 amino acids (aa) N-terminal ECD coupled to a 45 aa C-terminal transmembrane and cytoplasmic domain. Both soluble and transmembrane forms of the ITFG1 appear to exist. Human and mouse T cells treated with ITFG1 in vitro secreted the cytokines IFN-gamma, TNF-alpha and IL-10, while in vivo, ITFG1 was protective in a mouse acute graft-versus-host disease (GVHD) model. Based on invertebrate models, human ITFG1 likely serves as a cell adhesion molecule under certain circumstances. Over aa 1-566, human ITFG1 shares 89% and 88% aa sequence identity with mouse and rat ITFG1, respectively.
No product specific FAQs exist for this product, however you mayView all Antibody FAQs
Reviews for Human ITFG1 APC-conjugated Antibody
There are currently no reviews for this product. Be the first to review Human ITFG1 APC-conjugated Antibody and earn rewards!
Have you used Human ITFG1 APC-conjugated Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image