Human Latent TGF-beta  bp1 Alexa Fluor® 405-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB388V-100UG

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Human Latent TGF-beta  bp1 Alexa Fluor® 405-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human LTBP-1 from the large latent TGF-beta 1 complex.
Source
Monoclonal Mouse IgG1 Clone # 35409
Purification
Protein A or G purified
Immunogen
Human platelet-derived large latent TGF-β1 complex
Formulation
Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide
Label
Alexa Fluor 405 (Excitation= 405 nm, Emission= 421 nm)

Applications

Recommended Concentration
Sample
Western Blot
Optimal dilution of this antibody should be experimentally determined.
 
Immunoaffinity Purification
Optimal dilution of this antibody should be experimentally determined.
 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Latent TGF-beta bp1

TGF-beta  is synthesized as high molecular weight latent complexes. In platelets, the large latent TGF-beta 1 complex is composed of three components: mature TGF-beta 1 dimer; latency associated peptide; and a latent TGF-beta binding protein (LTBP) (1-3).The cDNAs for four binding proteins (LTBP-1, -2, -3 and -4) have now been cloned (4-5).

Entrez Gene IDs
4052 (Human)
Alternate Names
Latent TGFbeta bp1; Latent TGF-beta bp1; latent transforming growth factor beta binding protein 1; latent-transforming growth factor beta-binding protein 1; LTBP1; LTBP-1; MGC163161; TGF-beta1-BP-1; Transforming growth factor beta-1-binding protein 1

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