Human Latent TGF-beta bp1 Antibody
Human Latent TGF-beta bp1 Antibody Summary
Applications
under non-reducing conditions only
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Latent TGF-beta bp1
TGF-beta is synthesized as high molecular weight latent complexes. In platelets, the large latent TGF-beta 1 complex is composed of three components: mature TGF-beta 1 dimer; latency associated peptide; and a latent TGF-beta binding protein (LTBP) (1-3).The cDNAs for four binding proteins (LTBP-1, -2, -3 and -4) have now been cloned (4-5).
- Miyazono, K. et al. (1991) EMBO J. 10:1091.
- Moren, A. et al. (1994) J. Biol. Chem. 269:32469.
- Yin, W. et al. (1995) J. Biol. Chem. 270:10147.
- Kanzaki, T. et al. (1990) Cell 61:1051.
- Saharinen, J. et al. (1998) J. Biol. Chem. 273:18459.
Product Datasheets
Citations for Human Latent TGF-beta bp1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 9
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Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells
Authors: AJ Alshawaf, S Viventi, W Qiu, G D'Abaco, B Nayagam, M Erlichster, G Chana, I Everall, J Ivanusic, E Skafidas, M Dottori
Sci Rep, 2018-01-12;8(1):603.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
ATRA modulates mechanical activation of TGF-? by pancreatic stellate cells
Sci Rep, 2016-07-04;6(0):27639.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
Identification of the thiol isomerase-binding peptide, mastoparan, as a novel inhibitor of shear-induced transforming growth factor beta1 (TGF-beta1) activation.
Authors: Brophy T, Coller B, Ahamed J
J Biol Chem, 2013-03-05;288(15):10628-39.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Kidney transplantation: analysis of the expression and T cell-mediated activation of latent TGF-beta.
Authors: Willet J, Pichitsiri W, Jenkinson S, Brain J, Wood K, Alhasan A, Spielhofer J, Robertson H, Ali S, Kirby J
J Leukoc Biol, 2012-11-27;93(4):471-8.
Species: Human
Sample Types: Whole Cells, Whole Tissue
Applications: ICC, IHC-P -
Diverse functions of reactive cysteines facilitate unique biosynthetic processes of aggregate-prone interleukin-31.
Authors: Shen M, Siu S, Byrd S, Edelmann KH, Patel N, Ketchem RR, Mehlin C, Arnett HA, Hasegawa H
Exp. Cell Res., 2010-12-21;317(7):976-93.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Assembly of fibrillin microfibrils governs extracellular deposition of latent TGF beta.
Authors: Massam-Wu T, Chiu M, Choudhury R
J. Cell. Sci., 2010-08-10;123(0):3006-18.
Species: Human
Sample Types: Cell Lysates, Whole Cells
Applications: ICC, Immunoprecipitation, Western Blot -
Matrix association of latent TGF-beta binding protein-2 (LTBP-2) is dependent on fibrillin-1.
Authors: Vehvilainen P, Hyytiainen M, Keski-Oja J
J. Cell. Physiol., 2009-12-01;221(3):586-93.
Species: Human
Sample Types: Cell Culture Supernates, Whole Cells
Applications: ICC, Western Blot -
Syndromic and non-syndromic aneurysms of the human ascending aorta share activation of the Smad2 pathway.
Authors: Gomez D, Al Haj Zen A, Borges LF, Philippe M, Gutierrez PS, Jondeau G, Michel JB, Vranckx R
J. Pathol., 2009-05-01;218(1):131-42.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
Metastable tolerance to rhesus monkey renal transplants is correlated with allograft TGF-beta 1+CD4+ T regulatory cell infiltrates.
Authors: Torrealba JR, Katayama M, Fechner JH, Jankowska-Gan E, Kusaka S, Schultz JM, Hu H, Hamawy MM, Jonker M, Wubben J, Doxiadis G, Bontrop R, Burlingham WJ, Knechtle SJ
J. Immunol., 2004-05-01;172(9):5753-64.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Tissue Homogenates
Applications: Western Blot
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Average Rating: 3.7 (Based on 3 Reviews)
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Antibody was printed on custom arrays and incubated with fluorescently labeled human EDTA plasma
