Human Melanocortin-5 R/MC5R Alexa Fluor® 750-conjugated Antibody

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FAB8205S-100UG
R&D Systems Antibodies
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Human Melanocortin-5 R/MC5R Alexa Fluor® 750-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Stains human Melanocortin-5 R/MC5R transfected cells but not irrelevant transfectants in flow cytometry.
Source
Monoclonal Mouse IgG2a Clone # 821012
Immunogen
NS0 mouse myeloma cell line transfected with human Melanocortin-5 R/MC5R
Met1-Asp325
Accession # P33032
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 750 (Excitation= 749 nm, Emission= 775 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
HEK293 human embryonic kidney cell line transfected with human Melanocortin-5 R/MC5R and eGFP

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: Melanocortin-5 R/MC5R

Melanocortin 5R (MC5R) is a member of the melanocortin receptor family. The 325 amino acid G-protein-coupled 7-transmembrane glycoprotein is expressed in skeletal muscle, where engagement by a-melanocyte stimulating hormone increases glucose uptake and stimulates a thermogenic response. Expression is also found in sebaceous glands and other skin structures, and on selected hematopoietic cell lines. Human MC5R shares 80-81% amino acid sequence identity with mouse and rat MC5R.

Long Name
Melanocortin 5 Receptor
Entrez Gene IDs
4161 (Human); 17203 (Mouse); 25726 (Rat)
Alternate Names
MC2; MC-2; MC5; MC5R; MC5-R; melanocortin 5 receptor; melanocortin receptor 5; Melanocortin-5 R; melanocortin-5 receptor; Melanocortin5R; Melanocortin-5R

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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