Human Mesothelin Propeptide/MPF Biotinylated Antibody

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Product Details
Supplemental Products

Human Mesothelin Propeptide/MPF Biotinylated Antibody Summary

Species Reactivity
Detects human Mesothelin Propeptide/MPF in Western blots.  In Western blots, less than 1% cross-reactivity with mature recombinant human Mesothelin is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
Mouse myeloma cell line NS0-derived recombinant human Mesothelin Propeptide/MPF isoform 1
Accession # Q13421
Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Human Mesothelin Propeptide/MPF

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

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Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Size / Price
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Mesothelin

Mesothelin is a 40 kDa, 292 amino acid, GPI-linked glycoprotein found on normal mesothelial cells. It is also highly expressed in pancreatic, gastric and ovarian carcinomas. Mesothelin is synthesized as a preproprotein with a carboxy-terminal hydrophobic pro-region that is removed when a GPI-anchor is added. The amino‑terminal propeptide is cleaved by furin to release a33 kDa soluble protein that is also known as megakaryocyte potentiating factor (MPF). Mouse MPF has been shown to potentiate megakaryocyte colony forming activity of IL-3 in mouse bone marrow culture. The amino acid sequence of human MPF is 55% identical to that of mouse or rat MPF.

Entrez Gene IDs
10232 (Human); 56047 (Mouse); 60333 (Rat); 102130460 (Cynomolgus Monkey)
Alternate Names
CAK1 antigen; CAK1; megakaryocyte potentiating factor; Mesothelin; MPF; MPFSMRP; MSLN; Pre-pro-megakaryocyte-potentiating factor; SMR; soluble MPF mesothelin related protein

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