Human mGluR7 Alexa Fluor® 350-conjugated Antibody

Catalog # Availability Size / Price Qty
FAB4405U-100UG
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Human mGluR7 Alexa Fluor® 350-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human mGluR7. Stains human mGluR7 transfectants but not irrelevant transfectants.
Source
Monoclonal Mouse IgG2a Clone # 437310
Immunogen
HEK293 human embryonic kidney cell line transfected with human mGluR7
Gln35-Ile915
Accession # Q14831
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 350

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
A172 human glioblastoma cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: mGluR7

Metabotropic glutamate receptor 7 (mGluR7), also called GRM7 (G protein-coupled metabotropic glutamate receptor 7) is a 102 kDa member of the GRM family of 7‑transmembrane G protein-coupled receptors. mGluR7 is concentrated in the hippocampus and the amygdala and has a putative role in anxiety and spatial working memory. Within the 555 aa N-terminal extracellular domain, human mGluR7 shares > 99% aa identity with mouse, rat and dog mGluR7 and 90% aa identity with chicken mGluR7. Five isoforms (911‑924 aa) vary at the C‑terminus and are differentially expressed.

Long Name
Metabotropic Glutamate Receptor 7
Entrez Gene IDs
2917 (Human); 108073 (Mouse); 81672 (Rat)
Alternate Names
FLJ40498; glutamate receptor, metabotropic 7; GPRC1G; GRM7; metabotropic glutamate receptor 7; MGLU7; mGluR7; MGLUR7GPRC1GGLUR7

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