Human mGluR7 Alexa Fluor® 488-conjugated Antibody

  
  • Species Reactivity
    Human
  • Specificity
    Detects human mGluR7. Stains human mGluR7 transfectants but not irrelevant transfectants.
  • Source
    Monoclonal Mouse IgG2a Clone # 437310
  • Immunogen
    HEK293 human embryonic kidney cell line transfected with human mGluR7
    Gln35-Ile915
    Accession # Q14831
  • Formulation
    Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
  • Label
    Alexa Fluor 488
Applications
  •  
    Recommended
    Concentration
    Sample
  • Flow Cytometry
    0.25-1 µg/106 cells
    A172 human glioblastoma cell line
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
  • Shipping
    The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
  • Stability & Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: mGluR7

Metabotropic glutamate receptor 7 (mGluR7), also called GRM7 (G protein-coupled metabotropic glutamate receptor 7) is a 102 kDa member of the GRM family of 7‑transmembrane G protein-coupled receptors. mGluR7 is concentrated in the hippocampus and the amygdala and has a putative role in anxiety and spatial working memory. Within the 555 aa N-terminal extracellular domain, human mGluR7 shares > 99% aa identity with mouse, rat and dog mGluR7 and 90% aa identity with chicken mGluR7. Five isoforms (911‑924 aa) vary at the C‑terminus and are differentially expressed.

  • Long Name:
    Metabotropic Glutamate Receptor 7
  • Entrez Gene IDs:
    2917 (Human); 108073 (Mouse); 81672 (Rat)
  • Alternate Names:
    FLJ40498; glutamate receptor, metabotropic 7; GPRC1G; GRM7; metabotropic glutamate receptor 7; MGLU7; mGluR7; MGLUR7GPRC1GGLUR7
Related Research Areas
Isotype Controls
Description Application Cat# Citations Images  

Mouse IgG2A Alexa Fluor® 488-conjugated Antibody

Ctrl IC003G  
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Staining Reagents
Description Application Cat# Citations Images  

Flow Cytometry Staining Buffer (1X)

Flow FC001 6
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Flow Cytometry Mouse Lyse Buffer (10X)

Flow FC003 4
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Flow Cytometry Human Lyse Buffer (10X)

Flow FC002 1
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