Detection of mGluR7 in A172 Human Cell Line by Flow Cytometry. A172 human glioblastoma cell line was stained with Human mGluR7 Monoclonal Antibody (Catalog # MAB4405, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by Phycoerythrin-conjugated Anti-Mouse IgG |
F(ab')2 Secondary Antibody (Catalog # F0102B).
Metabotropic glutamate receptor 7 (mGluR7), also called GRM7 (G protein-coupled metabotropic glutamate receptor 7) is a 102 kDa member of the GRM family of 7‑transmembrane G protein-coupled receptors. mGluR7 is concentrated in the hippocampus and the amygdala and has a putative role in anxiety and spatial working memory. Within the 555 aa N-terminal extracellular domain, human mGluR7 shares > 99% aa identity with mouse, rat and dog mGluR7 and 90% aa identity with chicken mGluR7. Five isoforms (911‑924 aa) vary at the C‑terminus and are differentially expressed.
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