HABP1 (hyaluronan binding protein1; also p32 and gC1qR) is a 33 kDa member of the MAM33 family of proteins. It is widely expressed and found on/in endothelial cells, platelets and dendritic cells. It has multiple binding partners, including complement C1q, hyaluronan, vitronectin and ARF. Full-length mouse HABP1 proprecursor is 279 amino acid (aa) in length. It contains a 70 aa mitochondrial targeting sequence (aa 1‑70) that is cleaved to generate a 209 aa mature segment. A hyaluronan binding site lies between Lys116‑Lys125 and a Tyr phosphorylation site exists at Tyr184. Although the prosegment is usually cleaved, the intact proprecursor is associated with sperm. HABP1 reportedly forms noncovalent homotrimers. Over aa 72‑279, mouse HABP1 shares 99% and 91% aa identity with rat and human HABP1, respectively.
Human/Mouse/Rat HABP1/C1QBP Alexa Fluor™ Plus 405‑conjugated Antibody
R&D Systems | Catalog # AF5359AFP405
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Applications for Human/Mouse/Rat HABP1/C1QBP Alexa Fluor™ Plus 405‑conjugated Antibody
Western Blot
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Background: HABP1/C1QBP
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Product Specific Notices for Human/Mouse/Rat HABP1/C1QBP Alexa Fluor™ Plus 405‑conjugated Antibody
This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.
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