Human/Mouse/Rat HOMER1 Alexa Fluor™ Plus 555‑conjugated Antibody

R&D Systems | Catalog # FAB6889AFP555

R&D Systems
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Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

Western Blot

Label

Alexa Fluor Plus 555 (Excitation = 558 nm, Emission = 572 nm)

Antibody Source

Monoclonal Mouse IgG2B Clone # 666241
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Product Specifications

Specificity

Detects human HOMER1 in direct ELISAs.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human/Mouse/Rat HOMER1 Alexa Fluor™ Plus 555‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: HOMER1

HOMER1 is an approximately 48 kDa cytoplasmic protein that regulates the cell surface localization of neuronal mGluR1 and mGluR5 metabotropic glutamate receptors. It also functions in striated muscle mechanotransduction and excitation-contraction coupling by regulating the localization of transient receptor potential (TRP) channels and the coupling of ryanodine receptors to Cav1.2 calcium channels. Alternately spliced isoforms of human HOMER1 lack either the C-terminal half of the molecule (aa 178-354) or 130 aa following the WH1 domain (aa 99-228). Particular isoforms show distinct effects on hippocampal neuronal plasticity and the maintenance of extracellular glutamate levels in the prefrontal cortex. Within aa 73-82, human HOMER1 shares 100% aa sequence identity with mouse and rat HOMER1.

Long Name

Homer Protein Homolog 1

Alternate Names

HOMER1A, HOMER1B, HOMER1C, SYN47, Ves-1

Entrez Gene IDs

9456 (Human); 26556 (Mouse)

Gene Symbol

HOMER1

UniProt

Additional HOMER1 Products

Product Documents for Human/Mouse/Rat HOMER1 Alexa Fluor™ Plus 555‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human/Mouse/Rat HOMER1 Alexa Fluor™ Plus 555‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

Related Research Areas

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