Human NEDD8 Polyclonal Ab

R&D Systems | Catalog # A-812

Product is in the process of being discontinued.
R&D Systems
Discontinued Product
A-812 has been discontinued. View all NEDD8 products.

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG
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Product Specifications

Immunogen

Full-length, highly purified human NEDD8 protein

Specificity

Antibody does not cross-react with ubiquitn, SUMO, or ISG15 proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for Human NEDD8 Polyclonal Ab

Application
Recommended Usage

Western Blot

Recommended dilution range for Western blot analysis is 1:100 to 1:1000.  Non-functional for immunoprecipitation.

Formulation, Preparation, and Storage

Formulation

Boston Bio will fill in the Formulation info

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store unopened vial at -80°C. Avoid repeated freeze-thaw cycles. Aliquot antibody in small volumes prior to freezing.

Background: NEDD8

The ubiquitin-like protein NEDD8 is conjugated to targets by the NEDD8-specific E1 activating enzyme (APP-B1/UBA3), the Ubc12 E2 enzyme, and the ROC1/Rbx1 RING FINGER E3 ligase.  NEDD8 plays a critical regulatory role in cell proliferation and development, and modifies nearly all members of the cullin family. 

Long Name

Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8

Alternate Names

Neddylin, Rub1

Entrez Gene IDs

4738 (Human); 18002 (Mouse); 25490 (Rat)

Gene Symbol

NEDD8

Additional NEDD8 Products

Product Documents for Human NEDD8 Polyclonal Ab

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human NEDD8 Polyclonal Ab

For research use only

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