Detection of P2Y11/P2RY11 in HEK293 Human Cell Line Transfected with Human P2Y11/P2RY11 and eGFP by Flow Cytometry.
HEK293 human embryonic kidney cell line transfected with either (A) human P2Y11/P2RY11 or (B) irrelevant transfectants and eGFP was stained with Mouse Anti-Human P2Y11/P2RY11 Alexa Fluor® 647‑conjugated Monoclonal Antibody (Catalog # FAB9305R). Quadrant markers were set based on control antibody staining (Catalog # IC002R). View our protocol for Staining Membrane-associated Proteins.
Preparation and Storage
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
12 months from date of receipt, 2 to 8 °C as supplied.
belongs to the family of G protein-coupled receptors. This family has several
receptor subtypes with different pharmacological selectivity, which overlaps in
some cases, for various adenosine and uridine
nucleotides. P2RY11 is coupled to the stimulation of thephosphoinositide
and adenylyl cyclase pathways and behaves as a selective
purinoceptor. Naturally occuring read-through transcripts,resulting
from intergenic splicing between P2RY11 and an immediately upstream gene (PPAN,
encoding peter pan homolog), have been found. Variants in the P2RY11 gene have
been associated with narcolepsy.
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