Human Talin2 Alexa Fluor™ Plus 488‑conjugated Antibody

R&D Systems | Catalog # AF4738AFP488

R&D Systems
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Alexa Fluor Plus 488 (Excitation = 493 nm, Emission = 518 nm)

Antibody Source

Polyclonal Goat IgG
View all Talin2 Primary Antibodies »

Product Specifications

Specificity

Detects endogenous human Talin2 in Western blots. In Western blots, no cross-reactivity to recombinant human Talin1 was detected.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human Talin2 Alexa Fluor™ Plus 488‑conjugated Antibody

Application
Recommended Usage

Western Blot

Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Formulation

Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied

Background: Talin2

Talin2 (talus; Latin for ankle, the shape of a focal adhesion plaque complex) is a 240 kDa cytoplasmic focal adhesion molecule. It likely forms dimers that link integrins to the actin cytoskeleton. Human Talin2 is 2542 amino acids (aa) in length. It contains one globular N‑terminal FERM domain that binds integrin cytodomains (aa 88‑406), followed by an Ala-rich region (aa 861‑1193) and a C‑terminal actin-binding domain (aa 2321‑2530). Human Talin2 has three potential variants. Two show alternate start sites at Met19 and Met1153, while a third has an alternate start site at Met1608 accompanied by a deletion of aa 1748‑1790. Over aa’s 977‑1183, human Talin2 shares 99% and 97% aa identity with canine and mouse Talin2, respectively.

Alternate Names

ILWEQ, TLN2

Entrez Gene IDs

83660 (Human); 70549 (Mouse); 315776 (Rat)

Gene Symbol

TLN2

UniProt

Q9Y4G6

Additional Talin2 Products

Product Documents for Human Talin2 Alexa Fluor™ Plus 488‑conjugated Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human Talin2 Alexa Fluor™ Plus 488‑conjugated Antibody


This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com.

For research use only

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