ICI 118,551 hydrochloride

Tocris Bioscience | Catalog # 0821

Highly selective β2 inverse agonist
Tocris Bioscience

Key Product Details

Description

Highly selective β2 inverse agonist
View all Adrenergic beta 2 Receptor Inverse Agonists »

Product Description

ICI 118,551 hydrochloride is a very selective β2 adrenergic inverse agonist (Ki values are 1.2, 120 and 257 nM for β2, β1 and β3 receptors respectively). Active in vivo.

Licensing Information

Sold with the permission of AstraZeneca UK Ltd.

Product Specifications for ICI 118,551 hydrochloride

Molecular Weight

313.87

Formula

C17H27NO2.HCl

Storage

Store at RT

Purity

≥98% (HPLC)

Chemical Name

(±)-erythro-(S*,S*)-1-[2,3-(Dihydro-7-methyl-1H-inden-4-yl)oxy]-3-[(1-methylethyl)amino]-2-butanol hydrochloride

CAS Number

72795-01-8

PubChem ID

46704341

InChI Key

KBXMBGWSOLBOQM-MELYUZJYSA-N

SMILES

CC1=C(CCC2)C2=C(OC[C@@H](O)[C@H](C)NC(C)C)C=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 3.14 10
DMSO 3.14 10

Preparing Stock Solutions for ICI 118,551 hydrochloride

The following data is based on the product molecular weight 313.87.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.86 mL 159.30 mL 318.60 mL
0.5 mM 6.37 mL 31.86 mL 63.72 mL
1 mM 3.19 mL 15.93 mL 31.86 mL
5 mM 0.64 mL 3.19 mL 6.37 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 41 publications citing the usage of this product.

Product Documents for ICI 118,551 hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for ICI 118,551 hydrochloride

For research use only

Citations for ICI 118,551 hydrochloride

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