Potent fluorescent Smo antagonist (IC50
= 100 nM). Non-fluorescent analog IHR 1
Soluble to 5 mM in DMSO
Store at -20°C
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All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.
Fan et al.