Chemical Name: (2-[3-[1-(6-[[7-[[4-Chloro-3-[[4-(2,5-dichlorobenzamido)phenyl]carbamoyl]phenyl]amino]-7-oxoheptylamino]-6-oxohexyl]-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1-propen-1-yl]-1-ethyl-3,3-dimethyl-5-sulfo-3H-indolium, inner salt
Biological ActivityIHR-Cy3 is a potent fluorescent Smo antagonist (IC50 = 100 nM).
Non-fluorescent analog also available.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
The Hedgehog pathway effector smoothened exhibits signaling competency in the absence of ciliary accumulation.
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VersaClone cDNA Plasmids
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