Interleukin-17 Receptor E (IL-17RE) is a transmembrane protein that is expressed on mucosal epithelial cells, keratinocytes, Th17 cells, and gamma delta T cells. It associates with IL-17RA to form a heterodimeric receptor for IL-17C. Binding of IL-17C to this receptor complex promotes mucosal immunity by stimulating the production of anti-bacterial peptides and pro-inflammatory cytokines and chemokines. Additionally, IL-17C signaling regulates Th17 cell-dependent immune responses and has been suggested to contribute to psoriatic skin thickening, the progression of arthritis, and the pathogenesis of autoimmune diseases.
IL-17RE Antibody - BSA Free
Novus Biologicals | Catalog # NBP1-93925
![Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925]](https://beta-resources.rndsystems.com/images/products/IL-17RE-Antibody-Immunohistochemistry-Paraffin-NBP1-93925-img0006.jpg "Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925]")
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Key Product Details
Species Reactivity
Human
Applications
Immunohistochemistry, Immunohistochemistry-Paraffin
Label
Unconjugated
Antibody Source
Polyclonal Rabbit IgG
Format
BSA Free
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Product Specifications
Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: EKSHHISIPSPDISHKGLRSKRTQPSDPETWESLPRLDSQRHGGPEFSFDLLPEARAIRVTISSGPEVSVRLCHQWALECEELSSPYDVQKIVSGGHTVELPYEFLLPCLCMEASYLQEDTVRRKKCPFQSWPEAYGSDFWKSVHFTDYS
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Description
Novus Biologicals Rabbit IL-17RE Antibody - BSA Free (NBP1-93925) is a polyclonal antibody validated for use in IHC. Anti-IL-17RE Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
Scientific Data Images for IL-17RE Antibody - BSA Free
Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925]
Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925] - Staining of human duodenum shows strong membranous positivity in glandular cells.![Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925]](https://beta-resources.rndsystems.com/images/products/IL-17RE-Antibody-Immunohistochemistry-NBP1-93925-img0007.jpg "Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925]")
Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925]
Immunohistochemistry-Paraffin: IL-17RE Antibody [NBP1-93925] - Staining of human Fallopian tube shows strong cytoplasmic / membranous positivity in glandular cells.![IL-17RE Antibody - BSA Free Immunohistochemistry: IL-17RE Antibody - BSA Free [NBP1-93925]](https://beta-resources.rndsystems.com/images/products/nbp1-93925_rabbit-polyclonal-il-17re-antibody-30520257515821.jpg "Immunohistochemistry: IL-17RE Antibody - BSA Free [NBP1-93925]")
Immunohistochemistry: IL-17RE Antibody - BSA Free [NBP1-93925]
Staining of human skeletal muscle shows low positivity in myocytes as expected.![IL-17RE Antibody - BSA Free Immunohistochemistry: IL-17RE Antibody - BSA Free [NBP1-93925]](https://beta-resources.rndsystems.com/images/products/nbp1-93925_rabbit-polyclonal-il-17re-antibody-295202516453418.jpg "Immunohistochemistry: IL-17RE Antibody - BSA Free [NBP1-93925]")
Immunohistochemistry: IL-17RE Antibody - BSA Free [NBP1-93925]
Staining of human prostate shows moderate membranous positivity in glandular cells.Applications for IL-17RE Antibody - BSA Free
Application
Recommended Usage
Immunohistochemistry
1:50 - 1:200
Immunohistochemistry-Paraffin
1:50-1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Formulation, Preparation, and Storage
Purification
Affinity purified
Formulation
PBS (pH 7.2) and 40% Glycerol
Format
BSA Free
Preservative
0.02% Sodium Azide
Concentration
Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Background: IL-17RE
Long Name
Interleukin 17 Receptor E
Alternate Names
IL-17 RE, IL17RE, Il25r
Gene Symbol
IL17RE
Additional IL-17RE Products
Product Documents for IL-17RE Antibody - BSA Free
Product Specific Notices for IL-17RE Antibody - BSA Free
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
Citations for IL-17RE Antibody - BSA Free
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Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
- Antigen Retrieval Protocol (PIER)
- Antigen Retrieval for Frozen Sections Protocol
- Appropriate Fixation of IHC/ICC Samples
- Cellular Response to Hypoxia Protocols
- Chromogenic IHC Staining of Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Protocol
- Chromogenic Immunohistochemistry Staining of Frozen Tissue
- Detection & Visualization of Antibody Binding
- Fluorescent IHC Staining of Frozen Tissue Protocol
- Graphic Protocol for Heat-induced Epitope Retrieval
- Graphic Protocol for the Preparation and Fluorescent IHC Staining of Frozen Tissue Sections
- Graphic Protocol for the Preparation and Fluorescent IHC Staining of Paraffin-embedded Tissue Sections
- Graphic Protocol for the Preparation of Gelatin-coated Slides for Histological Tissue Sections
- IHC Sample Preparation (Frozen sections vs Paraffin)
- Immunofluorescent IHC Staining of Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Protocol
- Immunohistochemistry (IHC) and Immunocytochemistry (ICC) Protocols
- Immunohistochemistry Frozen Troubleshooting
- Immunohistochemistry Paraffin Troubleshooting
- Preparing Samples for IHC/ICC Experiments
- Preventing Non-Specific Staining (Non-Specific Binding)
- Primary Antibody Selection & Optimization
- Protocol for Heat-Induced Epitope Retrieval (HIER)
- Protocol for Making a 4% Formaldehyde Solution in PBS
- Protocol for VisUCyte™ HRP Polymer Detection Reagent
- Protocol for the Preparation & Fixation of Cells on Coverslips
- Protocol for the Preparation and Chromogenic IHC Staining of Frozen Tissue Sections
- Protocol for the Preparation and Chromogenic IHC Staining of Frozen Tissue Sections - Graphic
- Protocol for the Preparation and Chromogenic IHC Staining of Paraffin-embedded Tissue Sections
- Protocol for the Preparation and Chromogenic IHC Staining of Paraffin-embedded Tissue Sections - Graphic
- Protocol for the Preparation and Fluorescent IHC Staining of Frozen Tissue Sections
- Protocol for the Preparation and Fluorescent IHC Staining of Paraffin-embedded Tissue Sections
- Protocol for the Preparation of Gelatin-coated Slides for Histological Tissue Sections
- TUNEL and Active Caspase-3 Detection by IHC/ICC Protocol
- The Importance of IHC/ICC Controls
- Troubleshooting Guide: Immunohistochemistry
- View all Protocols, Troubleshooting, Illustrated assays and Webinars
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Associated Pathways
