IL-20 R alpha (or IL-20 R1) and IL-20 R beta (or IL-20 R2) belong to the class II cytokine receptor family. They form multiple heterodimeric signaling complexes that mediate IL-10 family class II cytokine signals. IL-20 R alpha heterodimerizes with IL-20 R beta to form the functional receptor for IL-19, IL-20 and IL-24. IL-20 R alpha also heterodimerizes with IL-10 R beta to form a functional receptor complex for IL-26, while IL-20 R beta heterodimerizes with IL-22 R to form functional IL-20 and IL-24 receptors. The IL-20 receptors are thought to mediate a number of physiological functions including apoptosis, hematopoiesis, and anti-tumor activities.
IL-20 R beta/FNDC6 Recombinant Protein Antigen
Novus Biologicals | Catalog # NBP2-68814PEP
Loading...
Key Product Details
Source
E. coli
Applications
Antibody Competition
Loading...
Product Specifications
Description
A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human IL-20 R beta/FNDC6.
Source: E. coli
Amino Acid Sequence: QFEFLVAYWRREPGAEEHVKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGE
Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)
This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.
Purity
>80% by SDS-PAGE and Coomassie blue staining
Predicted Molecular Mass
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Applications
Antibody Competition (10-100 molar excess)
Application Notes
This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP2-68814.
It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.
For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com
Protein / Peptide Type
Recombinant Protein Antigen
Formulation, Preparation, and Storage
NBP2-68814PEP
| Formulation | PBS and 1M Urea, pH 7.4. |
| Preservative | No Preservative |
| Concentration | Please see the vial label for concentration. If unlisted please contact technical services. |
| Shipping | The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below. |
| Stability & Storage | Store at -20C. Avoid freeze-thaw cycles. |
Background: IL-20 R beta
Long Name
Interleukin 20 Receptor beta
Alternate Names
DIRS1, FNDC6, IL-20R2, IL-20Rb, IL20R beta, IL20RB
Gene Symbol
IL20RB
Additional IL-20 R beta Products
Product Documents for IL-20 R beta/FNDC6 Recombinant Protein Antigen
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for IL-20 R beta/FNDC6 Recombinant Protein Antigen
This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.
Related Research Areas
Customer Reviews for IL-20 R beta/FNDC6 Recombinant Protein Antigen
There are currently no reviews for this product. Be the first to review IL-20 R beta/FNDC6 Recombinant Protein Antigen and earn rewards!
Have you used IL-20 R beta/FNDC6 Recombinant Protein Antigen?
Submit a review and receive an Amazon gift card!
$25/€18/£15/$25CAN/¥2500 Yen for a review with an image
$10/€7/£6/$10CAN/¥1110 Yen for a review without an image
Submit a review
Loading...