IL-27R alpha/WSX-1/TCCR Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-76728PEP

Novus Biologicals
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Key Product Details

Source

Synthetic

Applications

Antibody Competition
View all IL-27 R alpha/WSX-1/TCCR Proteins and Enzymes »

Product Specifications

Description

A blocking peptide containing 16 amino acids near the amino terminus of human TCCR.

Source: Synthetic

(Accession #: NP_004834)

Application Notes

This peptide is useful as a blocking peptide for NBP1-76728.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-76728PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: IL-27 R alpha/WSX-1/TCCR

Upon antigen challenge, T-helper cells differentiate into two functionally distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-g and lymphotoxin-b that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned. It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1. TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-g and Th1-dependent antibody IgG2a. TCCR is predominantly expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.

Long Name

Interleukin-27 Receptor Subunit alpha

Alternate Names

IL-27 R alpha, IL-27Ra, IL27R alpha, IL27RA, TCCR, WSX-1

Gene Symbol

IL27RA

Additional IL-27 R alpha/WSX-1/TCCR Products

Product Documents for IL-27R alpha/WSX-1/TCCR Antibody Blocking Peptide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IL-27R alpha/WSX-1/TCCR Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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FAQs for IL-27R alpha/WSX-1/TCCR Antibody Blocking Peptide

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  • Q: We need to know the sequence of the immunogen peptide. Are you able to supply me with this information?

    A: The peptide sequence is within amino acids 11-60 of NP_004834.1.

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Associated Pathways

Th1 Differentiation Pathway Th1 Differentiation Pathway Thumbnail