Iloprost

  ( 2 citations )    
Product Datasheet
Catalog Number:2038
Alternate Names:ZK 36374
Chemical Name:(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]pentanoic acid
Product Details
Citations (2)
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Biological Activity
Prostacyclin (PGI2) analog that binds with high affinity to IP, EP1 and EP3 receptors (Ki values are 11, 11, 56, 284, 619, 1035, 1870 and 6487 nM for IP, EP1, EP3, EP4, FP, DP, EP2 and TP receptors respectively). Inhibits platelet aggregation induced by collagen, thrombin and ADP (IC50 values are 0.24, 0.71 and 1.07 nM respectively).
Technical Data
  • M.Wt:
    360.49
  • Formula:
    C22H32O4
  • Solubility:
    Soluble in methyl acetate (supplied pre-dissolved - 5mg/ml)
  • Purity:
    >97
  • Storage:
    Desiccate at -20°C
  • CAS No:
    78919-13-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Iloprost include:

2 Citations: Showing 1 - 2
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  1. A human platelet calcium calculator trained by pairwise agonist scanning.
    Authors: Lee and Diamond
    Nat Commun  2015;11:e1004118
  2. Multiscale prediction of patient-specific platelet function under flow.
    Authors: Flamm Et al.
    Blood  2012;120:190

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