Catalog Number: 0986
Alternate Names: RS 21361
Chemical Name: 2-(1-Ethyl-2-indazoyl)methyl-1,4-benzodioxan hydrochloride
Biological Activity
A moderately potent, but highly selective α2-adrenoceptor antagonist, the only reported selective antagonist at the α2B-adrenoceptor not having potent α1-adrenoceptor antagonist activity.
Technical Data
  • M.Wt:
    280.75
  • Formula:
    C14H16N2O2.HCl
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
    >98%
  • Storage:
    Desiccate at RT
  • CAS No:
    81167-22-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Additional Information
Licensing Caveats:
Sold with the permission of Roche Bioscience
Background References
  1. Assessment of imiloxan as a selective α2B-adrenoceptor antagonist.
    Michel et al.
    Br.J.Pharmacol., 1990;99:560
  2. 2-(2-Imidazolylmethyl)-1,4-benzodioxans, a series of selective alpha2-adrenoceptor antagonists.
    Michel and Whiting
    Br.J.Pharmacol., 1981;74:255P

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