Imiquimod

Tocris Bioscience | Catalog # 3700

Toll-like receptor 7 (TLR7) agonist
Tocris Bioscience
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Key Product Details

Description

Toll-like receptor 7 (TLR7) agonist

Alternative Names

R 837

Product Description

Imiquimod is an immunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.

Product Specifications for Imiquimod

Molecular Weight

240.30

Formula

C14H16N4

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

CAS Number

99011-02-6

PubChem ID

57469

InChI Key

DOUYETYNHWVLEO-UHFFFAOYSA-N

SMILES

CC(C)CN2C=NC1=C(N)N=C3C(C=CC=C3)=C12

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

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Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 1.2 5 with gentle warming

Preparing Stock Solutions for Imiquimod

The following data is based on the product molecular weight 240.30.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.05 mM 83.23 mL 416.15 mL 832.29 mL
0.25 mM 16.65 mL 83.23 mL 166.46 mL
0.5 mM 8.32 mL 41.61 mL 83.23 mL
2.5 mM 1.66 mL 8.32 mL 16.65 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 24 publications citing the usage of this product.

Product Documents for Imiquimod

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Imiquimod

For research use only

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