Imiquimod

Catalog # Availability Size / Price Qty
3700/50
Imiquimod | CAS No. 99011-02-6 | Toll-like Receptor Agonists
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Description: Toll-like receptor 7 (TLR7) agonist
Alternative Names: R 837

Chemical Name: 1-(2-Methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine

Purity: ≥99%

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Biological Activity

Immunomodulator that displays antiviral and antitumor activity. Acts as a Toll-like receptor 7 (TLR7) agonist; stimulates proinflammatory cytokine production and activates NF-κB.

Technical Data

M.Wt:
240.3
Formula:
C14H16N4
Solubility:
Soluble to 5 mM in DMSO with gentle warming
Purity:
≥99%
Storage:
Store at +4°C
CAS No:
99011-02-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. The pharmacology of endosomal TLR agonists in viral disease.
    Averett et al.
    Biochem.Soc.Trans., 2007;35:1468
  2. A review of the applications of imiquimod: a novel immune response modifier.
    Syed et al.
    Exp.Opin.Pharmacother., 2001;2:877
  3. The antitumoral mode of action of imiq. and other imidazoquinolines.
    Schon and Schon
    Curr.Med.Chem., 2007;14:681

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