Immepip dihydrobromide

Tocris Bioscience | Catalog # 0932

Standard H3 agonist. Also H4 agonist
Tocris Bioscience

Key Product Details

Description

Standard H3 agonist. Also H4 agonist
View all Histamine H3 Receptor Agonists »

Product Description

Immepip dihydrobromide is a potent histamine H3 receptor agonist. Also binds to H4 receptors (Ki values are 0.4 and 9 nM at human recombinant H3 and H4 receptors respectively). Equipotent to or slightly more active than (R)-α-methylhistamine at H3 receptors.

Product Specifications for Immepip dihydrobromide

Molecular Weight

327.06

Formula

C9H15N3.2HBr

Storage

Desiccate at RT

Chemical Name

4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide

CAS Number

164391-47-3

PubChem ID

22315065

InChI Key

YGNJPNRDGXJQJX-UHFFFAOYSA-N

SMILES

Br.Br.C(C1CCNCC1)C1=CNC=N1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 32.71 100

Preparing Stock Solutions for Immepip dihydrobromide

The following data is based on the product molecular weight 327.06.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 3.06 mL 15.29 mL 30.58 mL
5 mM 0.61 mL 3.06 mL 6.12 mL
10 mM 0.31 mL 1.53 mL 3.06 mL
50 mM 0.06 mL 0.31 mL 0.61 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 17 publications citing the usage of this product.

Product Documents for Immepip dihydrobromide

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Immepip dihydrobromide

For research use only

Citations for Immepip dihydrobromide

Customer Reviews for Immepip dihydrobromide (1)

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  • Study of H4 receptor in the DGR neurons
    Name: Anonymous
    Species: Human
    Verified Customer | Posted 12/24/2019
    We applied 50 μM immepip and histamine to the dissociated DRG neurons in a chamber perfusion solution.
    To test the potential role of H4 receptor in the DRG neurons, we first investigated the effects of H4 agonist immepip dihydrobromide (immepip) and histamine to in dissociated DRG neurons.
    Immepip dihydrobromide 0932

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