Catalog Number: 0932
Chemical Name: 4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide
Biological Activity
Potent histamine H3 receptor agonist. Also binds to H4 receptors (Ki values are 0.4 and 9 nM at human recombinant H3 and H4 receptors respectively). Equipotent to or slightly more active than (R)-α-methylhistamine at H3 receptors.
Technical Data
  • M.Wt:
    327.06
  • Formula:
    C9H15N3.2HBr
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at RT
  • CAS No:
    164391-47-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow.
    Liu et al.
    Mol. Pharmacol., 2001;59:420
  2. Cardiovascular effects of selective agonists and antagonists of histamine H3 receptors in the anaesthetized rat.
    Coruzzi et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1995;351:569
  3. A new potent and selective histamine H3 receptor agonist.
    Vollinga et al.
    J.Med.Chem., 1994;37:332
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Immepip dihydrobromide include:

1 Citations: Showing 1 - 1

  1. Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.
    Authors: Gründemann Et al.
    Br J Pharmacol 2002;137:910

Have you used Immepip dihydrobromide?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information