Catalog Number: 0932
Chemical Name: 4-(1H-Imidazol-4-ylmethyl)piperidine dihydrobromide
Biological Activity
Potent histamine H3 receptor agonist. Also binds to H4 receptors (Ki values are 0.4 and 9 nM at human recombinant H3 and H4 receptors respectively). Equipotent to or slightly more active than (R)-α-methylhistamine at H3 receptors.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Storage:
    Desiccate at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Cloning and pharmacological characterization of a fourth histamine receptor (H4) expressed in bone marrow.
    Liu et al.
    Mol. Pharmacol., 2001;59:420
  2. Cardiovascular effects of selective agonists and antagonists of histamine H3 receptors in the anaesthetized rat.
    Coruzzi et al.
    Naunyn Schmiedebergs Arch.Pharmacol., 1995;351:569
  3. A new potent and selective histamine H3 receptor agonist.
    Vollinga et al.
    J.Med.Chem., 1994;37:332

The citations listed below are publications that use Tocris products. Selected citations for Immepip dihydrobromide include:

Showing Results 1 - 1 of 1

  1. Activation of the extraneuronal monoamine transporter (EMT) from rat expressed in 293 cells.
    Authors: Gründemann Et al.
    Br J Pharmacol
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details


Contact Information

Molarity Calculator
Calculate the mass, volume or concentration required for a solution

The molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) x Volume (L) x Molecular Weight (g/mol)
An example of a molarity calculation using the molarity calculator:
What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?

R&D Systems Guarantee

or select another batch:


Customer Information