Impentamine dihydrobromide

   
Product Datasheet
Catalog Number:1858
Alternate Names:VUF 4702
Chemical Name:4-(5-Aminopentyl)imidazole dihydrobromide
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Biological Activity
Potent and highly selective histamine H3 receptor antagonist (pA2 = 8.4); displays > 30000-fold selectivity over H1 and H2 receptors. Can act as a partial agonist in SK-N-MC cells expressing human H3 receptors. Produces antinociception, possibly via a non-H1, -H2 or -H3 receptor-mediated mechanism, following central administration in vivo.
Technical Data
  • M.Wt:
    315.05
  • Formula:
    C8H15N3.2HBr
  • Solubility:
    Soluble to 100 mM in water and to 100 mM in DMSO
  • Storage:
    Desiccate at RT
  • CAS No:
    149629-70-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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VersaClone cDNA Plasmids
Description Application Cat# Citations Images  

Mouse Histamine H3 R (NP_598610) VersaClone cDNA

RDC0728
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Human Histamine H3 R (NP_009163) VersaClone cDNA

RDC0344
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