INCB 024360-analog

Catalog # Availability Size / Price Qty
6007/10
6007/50
Cat.No. 6007 - INCB 024360-analog | C9H7ClFN5O2 | CAS No. 914471-09-3
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Description: Potent indoleamine 2,3-dioxygenase (IDO) inhibitor

Chemical Name: 4-Amino-N'-(3-chloro-4-fluorophenyl)-N-hydroxy-1,2,5-oxadiazole-3-carboximidamide

Purity: ≥99%

Product Details
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Biological Activity

Potent indoleamine 2,3-dioxygenase (IDO) inhibitor (IC50 values are 19 and 67 nM in enzymatic activity and HeLa cell assays, respectively). Decreases kynurenine levels in plasma and reduces tumor growth in vivo. Cell membrane permeable.

Technical Data

M.Wt:
271.64
Formula:
C9H7ClFN5O2
Solubility:
Soluble to 100 mM in DMSO and to 100 mM in ethanol
Purity:
≥99%
Storage:
Store at -20°C
CAS No:
914471-09-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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