Ipsapirone

Catalog # Availability Size / Price Qty
1869/10
1869/50
Ipsapirone | CAS No. 95847-70-4 | 5-HT1 Receptor Agonists
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Description: Selective 5-HT1A agonist
Alternative Names: TVX Q 7821

Chemical Name: 2-[4-[4-(2-Pyrimidinyl)-1-piperazinyl]butyl]-1,2-benzisothiazol-3(2H)-one-1,1-dioxide

Purity: ≥99%

Product Details
Citations (2)
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Reviews

Biological Activity

Selective 5-HT1A receptor agonist (Ki = 10 nM). Anxiolytic in vivo.

Technical Data

M.Wt:
401.48
Formula:
C19H23N5O3S
Solubility:
Soluble to 10 mM in DMSO
Purity:
≥99%
Storage:
Store at RT
CAS No:
95847-70-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and DArgic functions.
    Maj et al.
    J.Neural.Transm., 1987;70:1
  2. Binding of the putative anxiolytic TVX Q 7821 to hippocampal 5-hydroxytryptamine (5-HT) recognition sites.
    Glaser and Traber
    Naunyn-Schmied.Arch.Pharmacol., 1985;329:211
  3. Brain serotonin receptors as a target for the putative anxiolytic TVX Q 7821.
    Traber et al.
    Brain Res.Bull., 1984;12:741

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Citations for Ipsapirone

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