IRAK1/4 Inhibitor I

Tocris Bioscience | Catalog # 5665

IRAK4 and IRAK1 inhibitor
Tocris Bioscience

Key Product Details

Description

IRAK4 and IRAK1 inhibitor
View all IRAK Inhibitors »

Product Description

IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).

Product Specifications for IRAK1/4 Inhibitor I

Molecular Weight

395.41

Formula

C20H21N5O4

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide

CAS Number

509093-47-4

PubChem ID

11983295

InChI Key

QTCFYQHZJIIHBS-UHFFFAOYSA-N

SMILES

O=C(NC1=NC(C=CC=C2)=C2N1CCN3CCOCC3)C4=CC=CC([N+]([O-])=O)=C4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 7.91 20

Preparing Stock Solutions for IRAK1/4 Inhibitor I

The following data is based on the product molecular weight 395.41.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.2 mM 12.65 mL 63.23 mL 126.45 mL
1 mM 2.53 mL 12.65 mL 25.29 mL
2 mM 1.26 mL 6.32 mL 12.65 mL
10 mM 0.25 mL 1.26 mL 2.53 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 5 publications citing the usage of this product.

Product Documents for IRAK1/4 Inhibitor I

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for IRAK1/4 Inhibitor I

For research use only

Citations for IRAK1/4 Inhibitor I

Customer Reviews for IRAK1/4 Inhibitor I (1)

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  • Great for kinase assays and kinetics
    Name: Scott Scarneo
    Species: Human
    Assay Type: In Vitro
    Verified Customer | Posted 02/06/2019
    Easy to use for kinase assay to compare IRAK4 SAR analogs.
    IRAK1/4 Inhibitor I 5665

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