Home / IRAK Inhibitors / IRAK1/4 Inhibitor I

IRAK1/4 Inhibitor I

5665 1 Review Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
5665/10
5665/50
IRAK Inhibitors Small Molecule
1 Image
Description: IRAK4 and IRAK1 inhibitor

Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide

Purity: ≥98%

Product Details
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).

Technical Data

M.Wt:
395.41
Formula:
C20H21N5O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
509093-47-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
    Powers et al.
    Bioorg.Med.Chem.Lett., 2006;16:2842

Product Datasheets

Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for IRAK1/4 Inhibitor I

Average Rating: 5 (Based on 1 Review)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used IRAK1/4 Inhibitor I?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Great for kinase assays and kinetics
By Scott Scarneo on 02/06/2019
Species: Human

Easy to use for kinase assay to compare IRAK4 SAR analogs.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.