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IRAK1/4 Inhibitor I

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5665/50
IRAK1/4 Inhibitor I | CAS No. 509093-47-4 | IRAK Inhibitors
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Description: IRAK4 and IRAK1 inhibitor

Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide

Purity: ≥98%

Product Details
Reviews (1)
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).

Technical Data

M.Wt:
395.41
Formula:
C20H21N5O4
Solubility:
Soluble to 20 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
509093-47-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
    Powers et al.
    Bioorg.Med.Chem.Lett., 2006;16:2842

Product Datasheets

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Great for kinase assays and kinetics
By Scott Scarneo on 02/06/2019
Application: Species: Human

Easy to use for kinase assay to compare IRAK4 SAR analogs.

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