IRAK1/4 Inhibitor I
Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide
Purity: ≥98%
Biological Activity
IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Powers et al.
Bioorg.Med.Chem.Lett., 2006;16:2842
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Easy to use for kinase assay to compare IRAK4 SAR analogs.