IRAK1/4 Inhibitor I
Chemical Name: N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide
Purity: ≥98%
Biological Activity
IRAK1/4 Inhibitor I is an IRAK4 and IRAK1 inhibitor (IC50 values are 0.2 and 0.3 μM, respectively).Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4.
Powers et al.
Bioorg.Med.Chem.Lett., 2006;16:2842
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for IRAK1/4 Inhibitor I
The citations listed below are publications that use Tocris products. Selected citations for IRAK1/4 Inhibitor I include:
1 Citation: Showing 1 - 1
-
SIGIRR Mutation in Human Necrotizing Enterocolitis (NEC) Disrupts STAT3-Dependent microRNA Expression in Neonatal Gut.
Authors: Shahid Et al.
Cell Mol Gastroenterol Hepatol 2021;13:425-440
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for IRAK1/4 Inhibitor I
There are currently no reviews for this product. Be the first to review IRAK1/4 Inhibitor I and earn rewards!
Have you used IRAK1/4 Inhibitor I?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
