Highly selective ETB
endothelin receptor agonist (Ki
values are 0.016 and 1900 nM at ETB
receptors respectively). Discriminates two subpopulations of ETB
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All Tocris products are intended for laboratory research use only.
Endothelin; progress in pharmacology and physiology.
Haynes et al.
Suc-[Glu9, Ala11,15]-endothelin-1 (8-21), IRL 1620, identifies two populations of ETB receptors in guinea-pig bronchus.
Mazzoni et al.
Distinct subdomains of human endothelin receptors determine their selectivity to endothelinA-selective antagonist and endothelinB-selective agonists.
Sakamoto et al.
A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor.
Takai et al.
The citations listed below are publications that use Tocris products. Selected citations for IRL-1620 include:
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