antagonist, approximately 30-fold selective over 5-HT1A
. Also possesses affinity for β
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Interactions of isamoltane (CGP 361A), an anxiolytic phenoxypropanolamine derivative, with 5-HT1 receptor subtypes in the rat brain.
Waldmeier et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1988;337:609