5-HT1B Receptor Antagonists: Products

5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception.

"5-HT1B Receptor Antagonists" has 11 results in Products.
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GR 55562 dihydrochloride

5-HT1B antagonist

SB 224289 hydrochloride

Selective 5-HT1B antagonist

SB 216641 hydrochloride

Selective h5-HT1B antagonist


Selective r5-HT1B antagonist. Active in vivo

Isamoltane hemifumarate

5-HT1B antagonist

Cyanopindolol hemifumarate

5-HT1A/1B antagonist. Also β-adrenergic antagonist


β3 partial agonist. More active enantiomer of pindolol (Cat. No. 0994)

GR 127935 hydrochloride

Potent and selective 5-HT1B/1D antagonist

SDZ 21009

β-adrenoceptor antagonist. Also 5-HT1A/1B antagonist

LY 393558

Dual 5-HT1B/1D antagonist and 5-HT re-uptake inhibitor


β3 partial agonist
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