Catalog Number: 0235
Chemical Name: 1,2,3,6-Tetrahydro-4-pyridinecarboxylic acid hydrochloride
Biological Activity
Specific GABAA receptor agonist. Suppresses low magnesium induced seizure like events in organotypic hippocampal brain slices.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in water
  • Purity:
  • Storage:
    Store at RT
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Structure-activity studies on the inhibition of GABA binding to rat brain membranes by muscimol and related compounds.
    Krogsgaard-Larsen et al.
    J.Neurochem., 1978;30:1377
  2. Dihydromuscimol, thiomuscimol and related heterocyclic compounds as GABA analogues.
    Krogsgaard-Larsen et al.
    J.Neurochem., 1979;32:1717
  3. Effects of gamma-aminobutyric acid (GABA) agonists and a GABA uptake inhibitor on pharmacoresistant seizure like events in organotypic hippocampal slice cultures.
    Wahab et al.
    Epilepsy Res., 2009;86:113
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